Hyaline Degeneration: Understanding this Key Factor in Tissue Health
– Hyaline degeneration is the most common form of degeneration that can occur in a uterine leiomyoma.
– It is thought to occur in up to 60% of uterine leiomyomas.
– Hyaline degeneration happens when fibroids outgrow their blood supply.
– It involves the presence of homogeneous eosinophilic bands or plaques in the extracellular space.
– Radiographic features of hyaline degeneration on MRI are difficult to distinguish from non-degenerated fibroids.
– Areas of calcification can appear as signal voids on MRI.
– T1: isointense
– T2: hypointense
– T1 C+ (Gd): low enhancement in comparison to regular leiomyoma.
– Mostafa El-Feky and Yuranga Weerakkody had no financial relationships or disclosures at the time of the article.